The Israeli military said soldiers fired because the protests had turned into "riots". In other scenes, a small group lobs stones at an Israeli military vehicle on the other side of the fence.
"Yes, they go to the border fence; yes, they throw stones; yes, they throw Molotov cocktails, but you're dealing with one of the best equipped armies in the world", she said. He claimed Hamas leaders had been in the area encouraging the crowd.
In a statement Friday, the army said "hundreds of rioters" tried to burn the fence and infiltrate Israel.
Rights groups, the United Nations and the European Union have all criticized Israel's use of live fire against unarmed protesters.
Israel has rejected calls for an independent investigation into deaths along Gaza's border.
Israel says that would mean the end of the Jewish state, and accuses Gaza's Islamist rulers Hamas of using the protests as a pretext for violence.
EU, Iran oppose Macron's offer of new deal to Trump
Not now not in five years, not in 10 years, never", he told lawmakers. "We signed it, both the United States and France ". Now, back to the reality of fixing France . "Let us not create new walls ourselves on the other side", Macron said .
The ministry said three others were wounded in the incident Friday afternoon east of Gaza City.
Thousands gathered in the besieged Gaza Strip for the fifth-straight Friday as part of a mass sit-in known as the Great March of Return movement.
His remarks came as the Israeli forces used firearms against the most aggressive protesters, something that Tel Aviv attributed to the need to protect the state border.
"When we are fearless, we are getting closer toward martyrdom, martyrdom, martyrdom", he said.
The Israeli military has repeatedly said it will not allow Gazans to burst across the border.
However, Israel has come under heavy global criticism for allegedly using excessive force.
Palestinians in Gaza have organized each week along the Israeli border fence to protest displacement and what they consider land confiscation after Israel's founding.
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Gaza health officials say that four minors, including a 14-year-old boy, have been among the dead.
The UN High Commissioner for Human Rights Zeid Ra'ad al-Hussein on Friday called the loss of life deplorable and said a "staggering number" of injuries had been caused by live ammunition.
Erekat also took aim at the Trump administration and specifically called out U.S. envoy to the UN Nikki Haley, saying they serve as an aid to Israel's "systematic violations of its obligations under International Humanitarian Law and UN resolutions enjoying full impunity".
Palestinians were seen tearing down part of that wire barrier, and some made it to the actual border fencing.
Amnesty, which also supports an arms embargo for Palestinian armed groups, said in most fatal shooting analysed, victims were shot in the upper body, including the head and chest, some from behind.
Israeli soldiers, including snipers taking cover behind sand berms, have responded by firing tear gas, rubber-coated steel pellets and live rounds.
The Israeli military fighter jets have targeted six military targets belonging to Hamas's naval force in the northern Gaza Strip, said the Israeli Defense Forces (IDF). Tires were set ablaze, filling the air with thick smoke. The blockade has gutted Gaza's economy.
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Members of Hamas' honor guard carry the coffin of Palestinian scientist Fadi al-Batsh after it crossed into the Gaza Strip from Egypt at the Rafah crossing border, Thursday, April 26, 2018. The temporary opening is the second this month.