As play switched to the other end, Fonte brought down Suarez for a unsafe 25-yard free kick and the forward's low shot was well saved by Rui Patricio.
The only downside for Oscar Tabarez's side was the sight of Cavani limping off late on, raising a question mark over his fitness for next week's last eight showdown with the French in Nizhny Novgorod.
Just once did Uruguay fall asleep in their defensive duties, and it was for Pepe's aforementioned goal, however the 33-year-old forward was given one opening in the second half.
US FDA greenlights its first cannabis-based drug
Recent data suggests that it can potentially treat seizures, including Dravet syndrome and Lennox-Gastaut syndrome. But he said that won't affect Epidiolex's approval , since individual drugs often receive their own schedule.
"I believe that Cristiano Ronaldo is one of the best strikers in the world", the Uruguay coach told a pre-match press conference.
It was from another sort of dead-ball delivery that Portugal found a chink in the armour, Pepe equalising with a header from a corner after the break.
The forward had been instrumental in his side's performance to that point, having opened the scoring in the seventh minute after making an excellently timed run to get on the end of a cross into the area by fellow forward Luis Suarez.
Guedes made way for Andre Silva and goal hero Cavani, limping after a knock, was replaced by Cristhian Stuani befoe Guerreiro sent another effort over as the game entered its final quarter of an hour. We want to achieve this at the World Cup.
There were flashes from Ronaldo early but nothing compared to Luis Suarez and Edinson Cavani, as the famed Uruguay duo showed what can be achieved when you have a little support to lean on.
Talk Of Unity, But Little Progress At EU Mini-Summit On Migration
Mr Seehofer said last week that Mrs Merkel had two weeks to reach an agreement with her European partners on immigration. Italy's new far-right Interior Minister Matteo Salvini hit back at the French president.
Portugal had 61 percent of the possession and four times as many shots at goal as the Uruguayans, but Tabarez dismissed possession as a mere statistic and said what mattered was creating and converting chances.
The fearless Uruguay go marching on: The South Americans remain "dark-horses" for World Cup glory, but with four wins out of four, conceding just one goal in the process, they simply can not be overlooked.
The goals raised Cavani's total to three in the 2018 World Cup.
Ronaldo was involved somewhat in Portugal's goal, even if he didn't come close to getting a touch on the cross.
Priyanka Chopra says Nick Jonas is one of her 'favorite men'
Filmmaker Karan Johar and Indian former cricketer Sachin Tendulkar along with his wife Anjali Tendulkar also graced the ceremony. After the housewarming ceremony, Priyanka and Nick went out on a dinner date at an upscale restaurant in Mumbai .