Shaqiri completed the scoring in breathtaking fashion in MI, where Liverpool ended their International Champions Cup campaign with a resounding victory Saturday.
Managers Jurgen Klopp and Jose Mourinho have clashed in recent days over spending, and it was Klopp's Reds who came out on top in MI with goals from Sadio Mane, Daniel Sturridge, Sheyi Ojo and Xherdan Shaqiri on debut. I don't see the need [to sign a defender]. I was watching on television Chelsea against Inter and the people in Nice decided the beach was better.
"I think I am not going to get two". United's failure to bolster their resources and the absence of several key first team players following the World Cup has forced Mourinho to field several untested youngsters during the U.S. tour.
Manchester United was without stars Paul Pogba and Romelu Lukaku, both of whom are coming off deep World Cup runs.
Andreas Pereira cancelled out Mane's opening penalty with a fine free-kick to leave the sides level at the break, but United faltered in the second half.
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Liverpool players celebrating their lead against Man United. "We are not playing here to improve the team or improve our dynamic". We don't have wingers, we don't have strikers, he is the only who is here.
Mourinho still wants to strengthen his squad ahead of the transfer window closing on August 9.
"So what did this game give me?"
On Martial's absence, he said: "Anthony Martial has the baby and after the baby is born - handsome baby, full of health, thank God - he should be here and he is not here".
Mourinho meanwhile praised the contribution of senior players such as Sanchez, Juan Mata, Ander Herrera and Eric Bailly.
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Adding to United's injury woes is Serbian midfielder Nemanja Matic, who had undergone surgery after picking up an injury during the World Cup.
United's weakened team - including five players who didn't play a minute of Premier League football last season - is an indication of Mourinho's frustrations with the pre-season schedule.
"(Ander) Herrera, (Juan) Mata, Alexis (Sanchez), (Matteo) Darmian, these are the boys we have, they can not give more.
"Matic has had surgery". He is out for the start of the season.
Mourinho is keen to strengthen his squad before the transfer deadline with Tottenham's Toby Alderweireld and Harry Maguire, of Leicester, reported defensive targets. Mourinho said of Sanchez.
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"But I am not thinking I am going to have two". I think it's possible I am going to have one. "I wouldn't come. I wouldn't spend my money to see these teams", Mourinho said.