Sevastova will be advancing to her very first Grand Slam semifinal.
Only once in the professional era that began in 1968 had Japan had a men's and women's player in the quarterfinals at the same tournament. Kimiko Date was the last to do so at Wimbledon 1996.
CZECH Republic's Karolina Pliskova returns the ball against Serena Williams of the U.S. during their quarter-final.
"It's been a great battle", an exhausted Nadal said.
Peter Bodo has been covering tennis for over 35 years, mostly recently for ESPN. Mertens lobbed Stephens deep into deuce court, but Stephens, in full sprint, ran it down and hit a magnificent cross-court forehand victor with the stunned Mertens racing to the net.
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Both players had two chances to break in the third set, and the 15-40 chance that Isner missed at 2-1 ultimately proved to be his big opportunity.
However, one of Nishikori's wins came in the semi-finals in NY in 2014 when the Japanese star finished runner-up to Marin Cilic. She received a wild card into last year's U.S. Open and became the youngest player ever to make the girls' final. "I don't know how (Nick) Kyrgios and guys like that do it", Stephens said.
There was a wobble for Williams as she dropped her serve in the second set, coughing up one of her five double faults on break point as Pliskova narrowed the gap to 4-1.
The No. 20 seed moved from Japan to NY at age 3, and her deepest major run is coming at the same tournament she first visited as a child.
Sevastova, ranked 18th in the world, said she did not have many goals when she returned to tennis. Today, I served well at certain moments, so I think I'm on the right track.
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The 25-year-old looked off-colour and although the junior play on other courts was suspended Stephens and Sevastova carried on. "She admitted that it just wasn't the day".
The Latvian had no apparent power or pace, but she had the touch and variety to smother Stephens' game. On this afternoon, del Potro played particularly clean tennis, making only 14 unforced errors, less than a third as many as Isner's 52. "I had to try to come to the net, play some drop shots, move her, not let her play the game with her forehand and make the winners".
Osaka had consecutive 50-minute matches earlier in the tournament, including a 6-0, 6-0 thrashing of Aliaksandra Sasnovich in the third round.
The six-times champion at Flushing Meadows delivered 13 aces, including one on match point, and hit 34 winners in a 6-4 6-3 victory.
In the first set Sevastova won all the key drawings - the Latvian has implemented 2 out of 2 break points and his serve played 7 Stevens attempts to take the game at the reception. Williams punched her ticket to the semifinal with a win over No. 8 seed Karolína Pliskova at Arthur Ashe Stadium on Tuesday. So high were the temperatures on Tuesday. What's not working as well [as my down-the-line] is the opening ball towards the backhand of the opponent.
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